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UOP Researcher: New Drug Could Treat Some Heart Failure, Alzheimer’s


Researchers from the University of the Pacific School of Pharmacy have helped discover a possible breakthrough drug.

The drug could help prevent a rare form of heart failure.

Familial amyloid cardiomyopathy is an inherited condition that causes heart failure.

It affects about 4% of African Americans and about 20% of people over 80-years-old.

Researchers from the UOP School of Pharmacy, Stanford Medical School, and Scripps Research have discovered a drug called AG-10 which can stabilize proteins that sometimes attack the heart causing it to fail.

UOP Researcher Dr. Mamoun Alhamadsheh says the only treatment available now is a heart and liver transplant.

"There are so many issues with heart transplants as I mentioned, they cost about a million dollars for the heart, and about a half million dollars for the liver transplant, you need to find the match," says Alhamadsheh.

Dr. Alhamadsheh says AG-10 offers hope for about 50,000 patients who suffer from the condition.

"So from 3-4 years, if everything went fine, this could be a drug on the market,” says Alhamadsheh.

The drug also offers a possible treatment for Alzheimer's disease.

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